Good, J.A.D., Skoufias, D. and Kozielski, F. (2011) Elucidating the functionality of kinesins: An overview of small molecule inhibitors. Seminars in Cell and Developmental Biology, 22(9), pp. 935-945. (doi: 10.1016/j.semcdb.2011.09.023)
Full text not currently available from Enlighten.
Publisher's URL: http://dx.doi.org/10.1016/j.semcdb.2011.09.023
Abstract
Kinesin motor proteins are ubiquitously involved in multiple fundamental cellular processes, coordinating transport and mediating changes to cellular architecture. Thus, specific small molecule kinesin inhibitors can shed new light on the functions of kinesins and the dynamic roles in which they participate. Here we review the range of known inhibitors, their key characteristics, and specificity, and discuss their potential suitability for chemical genetics as starting points to further investigate complex kinesin-mediated processes
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Kozielski, Professor Frank and Good, Mr James |
Authors: | Good, J.A.D., Skoufias, D., and Kozielski, F. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
Journal Name: | Seminars in Cell and Developmental Biology |
ISSN: | 1084-9521 |
University Staff: Request a correction | Enlighten Editors: Update this record