Phototropin receptor kinase activation by blue light

Jones, M.A. and Christie, J.M. (2008) Phototropin receptor kinase activation by blue light. Plant Signaling and Behavior, 3(1), pp. 44-46. (doi: 10.4161/psb.3.1.4848)

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Phototropins (phot1 and phot2) are blue light-activated serine/threonine protein kinases that function to mediate a variety of adaptive processes that serve to optimize the photosynthetic efficiency of plants and thereby promote their growth. Light sensing by the phototropins is mediated by a repeated motif located within the N-terminal region of the protein designated the LOV domain. Although phototropins possess two LOV photosensors (LOV1 and LOV2), recent biophysical and structure-function analyses clearly indicate that the LOV2 domain plays a predominant role in regulating phototropin kinase activity owing to specific protein changes that occur in response to LOV2 photoexcitation. In particular, the central á-sheet scaffold plays a role in propagating the photochemical signal generated from within LOV2 to protein changes at the surface that are necessary for kinase activation.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Jones, Dr Matt and Christie, Professor John
Authors: Jones, M.A., and Christie, J.M.
Subjects:Q Science > QH Natural history > QH345 Biochemistry
Q Science > QH Natural history > QH301 Biology
College/School:College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
Journal Name:Plant Signaling and Behavior
ISSN (Online):1559-2324

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