Hampson, K. , Dobson, A., Kaare, M., Dushoff, J., Magoto, M., Sindoya, E. and Cleaveland, S. (2008) Rabies exposures, post-exposure prophylaxis and deaths in a region of endemic canine rabies. PLoS Neglected Tropical Diseases, 2(11), e339. (doi: 10.1371/journal.pntd.0000339)
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Publisher's URL: http://dx.doi.org/10.1371/journal.pntd.0000339
Abstract
Thousands of human deaths from rabies occur annually despite availability of effective vaccines for humans following exposure, and for disease control in domestic dog populations. We established a 5-year contact-tracing study in northwest Tanzania to investigate risk factors associated with rabies exposure and to determine why human deaths from canine rabies still occur. We found that children were at greater risk of being bitten and of developing rabies than adults and that incidence of bites by suspected rabid animals was higher in an area with larger domestic dog populations. A large proportion (>20%) of those bitten by rabid animals are not recorded in official records because they do not seek post-exposure prophylaxis (PEP), which is crucial for preventing the onset of rabies. Of those that seek medical attention, a significant proportion do not receive PEP because of the expense or because of hospital shortages; and victims who are poorer, and who live further from medical facilities, typically experience greater delays before obtaining PEP. Our work highlights the need to raise awareness about rabies dangers and prevention, particularly prompt PEP, but also wound management. We outline practical recommendations to prevent future deaths, stressing the importance of education, particularly in poor and marginalized communities, as well as for medical and veterinary workers.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Cleaveland, Professor Sarah and Hampson, Professor Katie |
Authors: | Hampson, K., Dobson, A., Kaare, M., Dushoff, J., Magoto, M., Sindoya, E., and Cleaveland, S. |
College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | PLoS Neglected Tropical Diseases |
Publisher: | Public Library of Science |
ISSN: | 1935-2727 |
ISSN (Online): | 1935-2735 |
Published Online: | 22 May 2008 |
Copyright Holders: | Copyright © 2008 The Authors |
First Published: | First published in PLoS Neglected Tropical Diseases 2(11):e339 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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