Gregson, N.A., Jones, D., Thomas, P.K. and Willison, H.J. (1991) Acute motor neuropathy with antibodies to GM1 ganglioside. Journal of Neurology, 238(8), pp. 447-451.
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Abstract
We describe a 52-year-old man who had an acute-onset purely motor neuropathy fulfilling the diagnostic criteria for the Guillain-Barré syndrome, in whom virtually complete spontaneous recovery occurred by 1 year, and in whom high titres of polyclonal serum antibody to GM1, GD1b, asialo-GM1 and lacto-N-tetraose were detected. The titre of IgM antibody to GM1 fell during the course of the disease with a concomitant rise in the IgG titre. This case adds to the widening spectrum of disease associated with anti-GM1 antibodies and provides further evidence for a relationship between anti-GM1 antibodies and motor system disease.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Willison, Professor Hugh |
Authors: | Gregson, N.A., Jones, D., Thomas, P.K., and Willison, H.J. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Journal of Neurology |
ISSN: | 0340-5354 |
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