Pathological gambling in Parkinson's disease - a review of the literature

Djamshidian, A., Cardoso, F., Grosset, D. , Bowden-Jones, H. and Lees, A.J. (2011) Pathological gambling in Parkinson's disease - a review of the literature. Movement Disorders, 26(11), pp. 1976-1984. (doi:10.1002/mds.23821)

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Publisher's URL: http://dx.doi.org/10.1002/mds.23821

Abstract

The prevalence of pathological gambling is 3.4% to 6% in treated Parkinson's disease, which is higher than the background population rate. In this review we discuss current evidence to indicate that dopamine agonists are much more likely to trigger this behavior than either L-dopa or selective monoamine oxidase B inhibitor monotherapy. New insights from recent behavioral and functional imaging studies and possible treatment approaches are also covered. A PubMed literature search using the terms "gambling" and "Parkin-son's disease," "impulse control disorder," "impulsive compulsive behaviour," "dopamine agonist," of individual dopamine agonists, and of ongoing drug trials, using <a href="http://www.clinicaltrials.gov/">www.clinicaltrials.gov</a> was carried out for the period up to January 2011.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Grosset, Dr Donald
Authors: Djamshidian, A., Cardoso, F., Grosset, D., Bowden-Jones, H., and Lees, A.J.
Subjects:R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Movement Disorders
Publisher:Wiley-Blackwell
ISSN:0885-3185
Published Online:09 June 2011

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