Ferre, S. et al. (2009) Building a new conceptual framework for receptor heteromers. Nature Chemical Biology, 5(3), pp. 131-134. (doi: 10.1038/nchembio0309-131)
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Publisher's URL: http://dx.doi.org/10.1038/nchembio0309-131
Abstract
Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Milligan, Professor Graeme |
| Authors: | Ferre, S., Baler, R., Bouvier, M., Caron, M. G., Devi, L. A., Durroux, T., Fuxe, K., George, S. R., Javitch, J. A., Lohse, M. J., Mackie, K., Milligan, G., Pfleger, K. D.G., Pin, J.-P., Volkow, N. D., Waldhoer, M., Woods, A. S., and Franco, R. |
| Subjects: | Q Science > QH Natural history > QH345 Biochemistry |
| College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
| Journal Name: | Nature Chemical Biology |
| Publisher: | Nature Publishing Group |
| ISSN: | 1552-4450 |
| ISSN (Online): | 1552-4469 |
| Related URLs: |
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