Harrington, J.A. and Jones, R.J. (2011) Management of metastatic castration-resistant prostate cancer after first-line docetaxel. European Journal of Cancer, 47(14), pp. 2133-2142. (doi: 10.1016/j.ejca.2011.04.036)
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Abstract
Although chemotherapy, based on docetaxel, is now established in the management of metastatic castration-resistant prostate cancer (mCRPC), until recently, there has been no treatment licensed for use in the second line in men whose disease progresses during or after docetaxel therapy. This article reviews the classes of agents that have shown potential in this setting, notably chemotherapy drugs, hormonal therapies, immunotherapies, anti-angiogenic drugs, and clusterin-targeted therapy.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Jones, Professor Robert |
Authors: | Harrington, J.A., and Jones, R.J. |
Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
Journal Name: | European Journal of Cancer |
ISSN: | 0014-2964 |
Published Online: | 10 June 2011 |
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