Transcription by RNA polymerase III: more complex than we though

White, R.J. (2011) Transcription by RNA polymerase III: more complex than we though. Nature Reviews Genetics, 12(7), pp. 459-463. (doi: 10.1038/nrg3001)

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Publisher's URL: http://dx.doi.org/10.1038/nrg3001

Abstract

RNA polymerase (Pol) III is highly specialized for the production of short non-coding RNAs. Once considered to be under relatively simple controls, recent studies using chromatin immunoprecipitation followed by sequencing (ChIP-seq) have revealed unexpected levels of complexity for Pol III regulation, including substantial cell-type selectivity and intriguing overlap with Pol II transcription. Here I describe these novel insights and consider their implications and the questions that remain

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:White, Prof Robert
Authors: White, R.J.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Nature Reviews Genetics
ISSN:1471-0056

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