Effect of pravastatin on cerebral infarcts and white matter lesions

ten Dam, V.H., van den Heuvel, D.M.J., van Buchem, M.A., Westendorp, R.G.J., Bollen, E.L.E.M., Ford, I. , de Craen, A.J.M. and Blauw, G.J. (2005) Effect of pravastatin on cerebral infarcts and white matter lesions. Neurology, 64(10), pp. 1807-1809. (doi: 10.1212/01.WNL.0000161844.00797.73)

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Abstract

The authors examined the effect of pravastatin 40 mg daily on the progression of ischemic brain lesions using repeated brain MRI. After a mean treatment period of 33 months, there was an increase in total ischemic lesion load of 1.1 cm3 (p < 0.001) in the 270 placebo-treated subjects and 1.1 cm3 (p < 0.001) in the 265 pravastatin-treated subjects. There was no difference between the two treatment groups (p = 0.73).

Item Type:Articles (Editorial)
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ford, Professor Ian
Authors: ten Dam, V.H., van den Heuvel, D.M.J., van Buchem, M.A., Westendorp, R.G.J., Bollen, E.L.E.M., Ford, I., de Craen, A.J.M., and Blauw, G.J.
Subjects:R Medicine > R Medicine (General)
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre
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Research Group:PROSPER Study Group
Journal Name:Neurology
ISSN:0028-3878
ISSN (Online):1526-632X

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