New Roles for Lysosomal Trafficking in Morphogen Gradient Sensing

Rainero, E. and Norman, J.C. (2011) New Roles for Lysosomal Trafficking in Morphogen Gradient Sensing. Science Signaling, 4(171), pe24. (doi:10.1126/scisignal.2002053)

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Publisher's URL: http://dx.doi.org/10.1126/scisignal.2002053

Abstract

The way in which cells recognize their position in a gradient of morphogen controls differentiation during embryogenesis. New findings indicate that the rate at which internalized morphogen receptors are trafficked to lysosomes is key to the accurate and precise sensing of morphogen gradients and the appropriate initiation of differentiation programs during development.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Norman, Professor James
Authors: Rainero, E., and Norman, J.C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Science Signaling
ISSN:1945-0877

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