(R)-salbutamol in the treatment of asthma and chronic obstructive airways disease

Patel, M. and Thomson, N.C. (2011) (R)-salbutamol in the treatment of asthma and chronic obstructive airways disease. Expert Opinion on Pharmacotherapy, 12(7), pp. 1133-1141. (doi: 10.1517/14656566.2011.571210)

Abstract

Areas covered: In this review the authors show that (R)-salbutamol alone (generically known as levosalbutamol) provides beneficial beta beta(2)-agonist effects at a cellular level and in experimental models of airways disease. In addition the authors demonstrate that (S)-salbutamol opposes the desirable effects of (R)-salbutamol and can actually cause features of asthma and COPD in vitro and in experimental asthma. Expert opinion: Despite this strong body of experimental evidence, (R)-salbutamol has not shown consistent superiority over (S)- or racemic salbutamol in human asthma or COPD

• Item Type: Articles (Editorial)
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Thomson, Professor Neil
• Authors: Patel, M., and Thomson, N.C.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: Expert Opinion on Pharmacotherapy
• ISSN: 1465-6566