Prevention of mother-to-child transmission of HIV in resource-rich and -poor settings

Mepham, S.O., Bland, R.M. and Newell, M.L. (2010) Prevention of mother-to-child transmission of HIV in resource-rich and -poor settings. BJOG: An International Journal of Obstetrics and Gynaecology, 118(2), pp. 202-218. (doi: 10.1111/j.1471-0528.2010.02733.x)

Abstract

Without prevention, a third of HIV-exposed infants acquire HIV in breastfeeding populations before, during, or after delivery through mother-to-child transmission (MTCT). Whereas MTCT is now a sentinel event in resource-rich countries with antiretroviral prophylaxis, caesarean section, and avoidance of breastfeeding, this is not yet the case in resource-poor settings because breastfeeding is crucial to infant survival. Recent advances in postpartum maternal and infant prophylaxis enables safer breastfeeding, and increasing numbers of women accessing treatment and prevention of MTCT services in sub-Saharan Africa is leading to optimism that MTCT could be eliminated here also, as reflected in the UNAIDS target of 2015.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Bland, Dr Ruth
• Authors: Mepham, S.O., Bland, R.M., and Newell, M.L.
• College/School: College of Medical Veterinary and Life Sciences
• Journal Name: BJOG: An International Journal of Obstetrics and Gynaecology
• Publisher: Wiley-Blackwell Publishing Ltd.
• ISSN: 1470-0328
• ISSN (Online): 1471-0528