Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study

Frotzler, A., Coupaud, S., Perret, C., Kakebeeke, T.H., Hunt, K.J. and Eser, P. (2009) Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study. Journal of Rehabilitation Medicine, 41(4), pp. 282-285. (doi: 10.2340/16501977-0321)

Abstract

Objective: To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after de-training or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury (SCI). Subjects: Five subjects with motor-sensory complete SCI (age 38.6 years, lesion duration 11.4 years) were included. Four subjects stopped FES-cycling completely after the training phase whereas one continued reduced FES-cycling (2-3 times/week, for 30min). Methods: Bone and muscle parameters were assessed in the legs using peripheral quantitative computed tomography at six and twelve months after cessation of high-volume FES-cycling. Results: Gains achieved in the distal femur by high-volume FES-cycling were partly maintained at one year of detraining: 73.0% in trabecular bone mineral density (BMD), 63.8% in total BMD, 59.4% in bone mineral content and 22.1% in muscle cross-sectional area (CSAmuscle) in the thigh. The subject who continued reduced FES-cycling maintained 96.2% and 95.0% of the previous gain in total and trabecu-lar BMD, and 98.5% in CSAmuscle. Conclusion: Bone and muscle benefits achieved by one year of high-volume FES-cycling are partly preserved after 12 months of detraining whereas reduced cycling maintains bone and muscle mass gained. This suggests that high-volume FES-cycling has clinical relevance for at least 1y after detraining.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Coupaud, Dr Sylvie and Hunt, Prof Kenneth
• Authors: Frotzler, A., Coupaud, S., Perret, C., Kakebeeke, T.H., Hunt, K.J., and Eser, P.
• Subjects: R Medicine > R Medicine (General)
• College/School: College of Science and Engineering > School of Engineering > Biomedical Engineering; College of Science and Engineering > School of Engineering > Systems Power and Energy
• Journal Name: Journal of Rehabilitation Medicine
• Publisher: Stiftelsen Rehabiliteringsinformation (Foundation for Rehabilitation Information)
• ISSN: 1650-1977
• Copyright Holders: Copyright © 2009 Stiftelsen Rehabiliteringsinformation (Foundation for Rehabilitation Information)
• First Published: First published in Journal of Rehabilitation Medicine 41(4):282-285
• Publisher Policy: Reproduced with permission of the publisher