Webster, E., McIntyre, J., Choonara, I. and Preston, T. (2004) The Caffeine Breath Test and CYP1A2 Activity in Children. Paediatric and Perinatal Drug Therapy, 5(1), pp. 28-33.
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Publisher's URL: http://www.librapharm.com/journals/paediatric/paediatric.php
Abstract
The caffeine breath test is a non-invasive method of studying CYP1A2 activity that is suitable for children from the ages of 3 years upwards. It involves the oral administration of a stable isotope and the collection of breath samples for a period of 2 hours. Breath samples are analysed by continuous flow isotope ratio mass spectrometry. It has been used to study both drug interactions and the effect of disease on drug metabolism.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Preston, Professor Tom |
Authors: | Webster, E., McIntyre, J., Choonara, I., and Preston, T. |
Subjects: | R Medicine > RJ Pediatrics |
College/School: | College of Science and Engineering > Scottish Universities Environmental Research Centre |
Journal Name: | Paediatric and Perinatal Drug Therapy |
Publisher: | LibraPharm |
ISSN: | 1463-0095 |
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