Jones, J.H., Attaie, M., Maroo, S., Neumann, D., Perry, R. and Donaldson, M.D.C. (2010) Heterogeneous tissue in the thyroid fossa on ultrasound in infants with proven thyroid ectopia on isotope scan—a diagnostic trap. Pediatric Radiology, 40(5), pp. 725-731. (doi: 10.1007/s00247-009-1492-2)
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Publisher's URL: http://dx.doi.org/10.1007/s00247-009-1492-2
Abstract
<p><b>Background</b></p> <p>Thyroid imaging is of proven help in establishing a diagnosis of congenital hypothyroidism in infants. US often shows tissue in the thyroid fossa when radionuclide scintigraphy reveals only ectopic uptake.</p> <p><b>Objective</b></p> <p>Our hypothesis was that the use of US alone could lead to the mistaken diagnosis of normal or dysplastic thyroid in cases of scintigraphy-proven thyroid ectopia.</p> <p><b>Materials and methods</b></p> <p>We undertook a detailed retrospective review and analysis of imaging and concurrent biochemistry in infants with thyroid ectopia, confirmed by radionuclide scintigraphy.</p> <p><b>Results</b></p> <p>Eighteen infants had thyroid ectopia; ten of the original US reports had suggested that cervical thyroid tissue was present. Review showed bilateral tissue in the thyroid fossa in all that was non-thyroidal in nature since, apart from showing no radionuclide uptake, it exhibited some or all of the following typical features: hyperechogenicity, heterogeneity, small size, poor vascularity, and anechoic and/or hypoechoic cysts. Also, extension of the tissue both around and behind the large cervical blood vessels was a universal finding.</p> <p><b>Conclusion</b></p> <p>Considerable experience is required to interpret neonatal thyroid US. We caution against diagnosing a dysplastic/hypoplastic thyroid gland in situ on the basis of US alone, particularly if the tissue exhibits any of the non-thyroidal features described.</p>
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Jones, Mr Jeremy and Donaldson, Dr Malcolm and Perry, Dr Rebecca |
| Authors: | Jones, J.H., Attaie, M., Maroo, S., Neumann, D., Perry, R., and Donaldson, M.D.C. |
| Subjects: | R Medicine > R Medicine (General) |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities |
| Journal Name: | Pediatric Radiology |
| Publisher: | Springer |
| ISSN: | 0301-0449 |
| ISSN (Online): | 1432-1998 |
| Published Online: | 12 January 2010 |
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