Milner-White, E.J. and Russell, M. (2008) Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct. Biology Direct, 3(3), pp. 1-9. (doi: 10.1186/1745-6150-3-3)
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Publisher's URL: http://dx.doi.org/10.1186/1745-6150-3-3
Abstract
Considering that short, mainly heterochiral, polypeptides with a high glycine content are expected to have played a prominent role in evolution at the earliest stage of life before nucleic acids were available, we review recent knowledge about polypeptide three-dimensional structure to predict the types of conformations they would have adopted. The possible existence of such structures at this time leads to a consideration of their functional significance, and the consequences for the course of evolution.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Milner-White, Professor E |
Authors: | Milner-White, E.J., and Russell, M. |
Subjects: | Q Science > QH Natural history > QH301 Biology |
College/School: | College of Medical Veterinary and Life Sciences |
Journal Name: | Biology Direct |
Publisher: | BioMed Central |
ISSN: | 1745-6150 |
Copyright Holders: | 2008 © Copyright BioMed Central |
First Published: | First published in Biology Direct 3(3):1-9 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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