Shankar, V., Roberts, F. and Ramaesh, K. (2010) Histopathological Changes of Cornea in Long-Term Sympathetic Ophthalmitis. Cornea, 29(11), pp. 1287-1290. (doi: 10.1097/ICO.0b013e3181e843c8)
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Publisher's URL: http://dx.doi.org/10.1097/ICO.0b013e3181e843c8
Abstract
Purpose: To report the histopathological changes occurring in the cornea in sympathetic ophthalmitis. Methods: Observational case series of 3 patients with sympathetic ophthalmitis who were treated with penetrating keratoplasty. We report the histopathological features of the cornea. Results: In all 3 cases, the epithelium was edematous and bullous with extensive loss of the Bowman layer and calcification of the superficial stroma in all the 3 eyes. The deep stroma was unremarkable in appearance. Descemet membrane showed thickening in 2 of the corneas with nodular excrescences and folds noted in 1 of the specimens. The endothelium was attenuated with some residual cells containing pigment granules in 1 case. Conclusions: Endothelial loss and development of bullous keratopathy associated with band keratopathy are predominate histopathological features of the cornea. These changes are nonspecific and reflect a chronic anterior uveitis.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Roberts, Dr Fiona |
| Authors: | Shankar, V., Roberts, F., and Ramaesh, K. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | Cornea |
| ISSN: | 0277-3740 |
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