Clinical and topographic magnetic resonance imaging characteristics of suspected thalamic infarcts in 16 dogs

Gon, R., Carrera, I., Garosi, L., Smith, P.M., Fraser McConnell, J. and Penderis, J. (2011) Clinical and topographic magnetic resonance imaging characteristics of suspected thalamic infarcts in 16 dogs. Veterinary Journal, 188(1), pp. 39-43. (doi: 10.1016/j.tvjl.2010.03.024)

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Abstract

Sixteen dogs with acute-onset, non-progressive signs of brain dysfunction and magnetic resonance imaging (MRI) characteristics compatible with thalamic infarction are described. Topographically the MRI lesions could be grouped in three thalamic regions, namely, paramedian (8/16), extensive dorsal (5/16) and ventrolateral (3/16). Paramedian lesions resulted in signs typical of vestibular dysfunction. Extensive dorsal lesions were associated with vestibular ataxia, circling and contralateral menace response deficits. Ventrolateral lesions resulted in circling and contralateral proprioceptive deficits. In several dogs, regions other than the thalamus were also affected: four extended into the midbrain; six extended to the internal capsule, and two dogs had a second lesion in the cerebellum. Three clinical syndromes were identified in association with thalamic infarction. These signs varied somewhat, most likely because lesions were not confined to specific nuclear boundaries and involved different combinations of thalamic nuclei.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Penderis, Professor Jacques and Carrera, Miss Inez
Authors: Gon, R., Carrera, I., Garosi, L., Smith, P.M., Fraser McConnell, J., and Penderis, J.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Veterinary Journal
Publisher:Elsevier Ltd
ISSN:1090-0233
ISSN (Online):1532-2971
Published Online:24 April 2010

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