Pollard, P.J. and Kranc, K.R. (2010) Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword. Cell Stem Cell, 7(3), pp. 276-278. (doi: 10.1016/j.stem.2010.08.006)
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Publisher's URL: http://dx.doi.org/10.1016/j.stem.2010.08.006
Abstract
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signaling in HSCs remains unclear. In this issue of Cell Stem Cell, Takubo et al. (2010) and Simsek et al. (2010) demonstrate that hypoxia regulates the metabolic state of HSCs and protects their integrity by controlling HIF-1 alpha.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Kranc, Professor Kamil |
| Authors: | Pollard, P.J., and Kranc, K.R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Cell Stem Cell |
| ISSN: | 1934-5909 |
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