A genotype and phenotype database of genetically modified malaria-parasites

Janse, C.J., Kroeze, H., van Wigcheren, A., Mededovic, S., Fonager, J., Franke-Fayard, B., Waters, A.P. and Khan, S.H. (2010) A genotype and phenotype database of genetically modified malaria-parasites. Trends in Parasitology, 27(1), pp. 31-39. (doi:10.1016/j.pt.2010.06.016)

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Publisher's URL: http://dx.doi.org/10.1016/j.pt.2010.06.016

Abstract

The RMgm database, www.pberghei.eu, is a web-based, manually curated, repository containing information on genetically modified rodent-malaria parasites. It provides easy and rapid access to information on the genotype and phenotypeáof mutant and reporter parasites. The database also contains information on unpublished mutants without a clear phenotype and negative trials to disrupt genes. Information can be searched using pre-defined key features, such as phenotype, life-cycle stage, gene model, gene-tags and mutations. The information relating to the mutants is reciprocally linked to PlasmoDB and GeneDB. Access to mutant-parasite information, and gene function/ontology inferred from mutant phenotypes provides a timely resource aimed at enhancing research into Plasmodium gene function and (systems) biology

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Waters, Professor Andy
Authors: Janse, C.J., Kroeze, H., van Wigcheren, A., Mededovic, S., Fonager, J., Franke-Fayard, B., Waters, A.P., and Khan, S.H.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Trends in Parasitology
ISSN:1471-4922

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