Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy

Friborg, J. T., Jarrett, R.F. , Koch, A., Garred, P., Freeland, J. M. L., Andersen, A. and Melbye, M. (2010) Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy. Clinical and Vaccine Immunology, 17(9), pp. 1484-1487. (doi: 10.1128/CVI.00527-09)

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Publisher's URL: http://dx.doi.org/10.1128/CVI.00527-09

Abstract

In a cohort study of children < 4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Freeland, Mrs June and Jarrett, Professor Ruth
Authors: Friborg, J. T., Jarrett, R.F., Koch, A., Garred, P., Freeland, J. M. L., Andersen, A., and Melbye, M.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Journal Name:Clinical and Vaccine Immunology
ISSN:1556-6811

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