Preeclampsia and future maternal health

Carty, D.M., Delles, C. and Dominiczak, A.F. (2010) Preeclampsia and future maternal health. Journal of Hypertension, 28(7), pp. 1349-1355. (doi: 10.1097/HJH.0b013e32833a39d0)

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Publisher's URL: http://dx.doi.org/10.1097/HJH.0b013e32833a39d0

Abstract

Preeclampsia is a multisystem disorder that complicates 3-8% of pregnancies in the Western world, and is a major source of morbidity and mortality worldwide. Although it is a disease unique to pregnancy, evidence has mounted in recent years that preeclampsia has important implications for future maternal health, in particular cardiovascular health. In this review we examine epidemiological evidence for this relationship, and examine potential mechanisms such as insulin resistance, genetic factors and endothelial dysfunction that may explain the relationship. In addition we explore potential future avenues of research into the field, such as genomics, proteomics and metabolomics.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dominiczak, Professor Anna and Delles, Professor Christian and Carty, Dr David
Authors: Carty, D.M., Delles, C., and Dominiczak, A.F.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:Journal of Hypertension
ISSN:0263-6352

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