Kennedy, A.R., Kerr, W.J., Paterson, L.C. and Sutherland, A. (2010) A Tetrahydropentaleno[1,6a-a]naphthalen-4(2H)-one of Defined Relative Stereochemistry for Use Towards Agariblazeispirol C. Acta Crystallographica. Section D: Biological Crystallography, 66(9), 0473-0474. (doi: 10.1107/S0108270110031781)
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Abstract
Towards the synthesis of the novel natural product Agariblazeispirol C, (5aR*,11bR*)-9-methoxy-3,8,11b-trimethyl-5,6,7,11b-tetrahydro-1H-pentaleno[1,6a-a]naphthalen-4(2H)-one, C20H24O2, has been prepared at a key stage of the preparative programme. The structure shows the desired stereochemical outcome of the central cyclization protocol, viz. a syn-relationship between the aliphatic methyl group on the 11b-position and the methylene group on the 5a-position [C-C-C-C = -34.57 (18)degrees].
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Sutherland, Professor Andrew |
Authors: | Kennedy, A.R., Kerr, W.J., Paterson, L.C., and Sutherland, A. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Acta Crystallographica. Section D: Biological Crystallography |
Publisher: | Wiley-Blackwell Publishing, Inc. |
ISSN: | 0907-4449 |
ISSN (Online): | 1399-0047 |
Published Online: | 01 January 2010 |
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