Current directions in co-crystal growth

Blagden, N., Berry, D. J., Parkin, A., Javed, H., Ibrahim, A., Gavan, P. T., De Matos, L. L. and Seaton, C. C. (2008) Current directions in co-crystal growth. New Journal of Chemistry, 32(10), pp. 1659-1672. (doi: 10.1039/b803866j)

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Abstract

In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies.

Item Type:Articles
Keywords:3,5-DINITROBENZOIC ACID ACTIVE PHARMACEUTICAL INGREDIENTS CAMBRIDGE STRUCTURAL DATABASE CARBOXYLIC-ACIDS CO-CRYSTAL CO-CRYSTALS COCRYSTALS CRYSTAL CRYSTAL-GROWTH GROWTH HYDROGEN-BOND PATTERNS IN-SITU MOLECULAR-COMPLEXES nucleation PHASE-DIAGRAMS SOLID-STATE STATE STRATEGIES STRATEGY SUPRAMOLECULAR SYNTHONS TEMPLATE THERMODYNAMIC PROPERTIES XRD
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Parkin, Dr Andrew
Authors: Blagden, N., Berry, D. J., Parkin, A., Javed, H., Ibrahim, A., Gavan, P. T., De Matos, L. L., and Seaton, C. C.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:New Journal of Chemistry
ISSN:1144-0546

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