Harnett, W. and Harnett, M. M. (2010) Helminth-derived immunomodulators: can understanding the worm produce the pill? Nature Reviews Immunology, 10(4), pp. 278-284. (doi: 10.1038/nri2730)
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Abstract
Helminths may protect humans against allergic and autoimmune diseases and, indeed, defined helminth-derived products have recently been shown to prevent the development of such inflammatory diseases in mouse models. Here, we propose that helminth-derived products not only have therapeutic potential but can also be used as unique tools for defining key molecular events in the induction of an anti-inflammatory response and, therefore, for defining new therapeutic targets
| Item Type: | Articles |
|---|---|
| Keywords: | allergy autoimmune disease BLOOD C-TYPE LECTINS CONTAINING SECRETED PRODUCT CUTTING EDGE DENDRITIC CELL ACTIVATION DISEASE DISEASES DRIVES TH2 RESPONSES ENGLAND EVENTS HOST IMMUNE-RESPONSES Human HUMANS IN-VIVO INFLAMMATORY RESPONSES MODEL PRODUCT PROTEIN-KINASE Scotland TOLL-LIKE RECEPTORS |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Harnett, Professor Margaret |
| Authors: | Harnett, W., and Harnett, M. M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Nature Reviews Immunology |
| ISSN: | 1474-1733 |
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