The detection of Bovine Papillomavirus type 1 DNA in flies

Finlay, M., Yuan, Z.Q., Burden, F., Trawford, A., Morgan, I.M., Campo, M.S. and Nasir, L. (2009) The detection of Bovine Papillomavirus type 1 DNA in flies. Virus Research, 144(1-2), pp. 315-317. (doi: 10.1016/j.virusres.2009.04.015)

Abstract

BPVs are double stranded DNA viruses that can infect several species other than the natural host, cattle, including equids. In equids, BPV-1, and, less commonly BPV-2, infection gives rise to fibroblastic tumours of the skin. Whilst a causal relationship between BPV-1/2 and equine sarcoids is now well established, how the disease is transmitted is not known. In this study we show BPV-1 DNA can be detected in flies trapped in the proximity of sarcoid-affected animals. Sequence analysis of the BPV-1 LCR from flies indicates that flies harbour BPV-1 LCR sequence variants 11 and IV which are commonly detected in equine sarcoids. These data suggest that flies may be able to transmit BPV-1 between equids.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Campo, M Saveria and Nasir, Professor Lubna and Morgan, Professor Iain and Yuan, Dr Zhengqiang
• Authors: Finlay, M., Yuan, Z.Q., Burden, F., Trawford, A., Morgan, I.M., Campo, M.S., and Nasir, L.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine; College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: Virus Research
• ISSN: 0168-1702