Biodegradable polymer tubes with litho graphically controlled 3D micro- and nanotopography

Seunarine, K., Meredith, D.O., Riehle, M.O. , Wilkinson, C.D.W. and Gadegaard, N. (2008) Biodegradable polymer tubes with litho graphically controlled 3D micro- and nanotopography. Microelectronic Engineering, 85(5-6), pp. 1350-1354. (doi: 10.1016/j.mee.2008.02.002)

Abstract

We introduce a novel scaffold fabrication process for making tubular constructs for vascular tissue engineering. Every aspect of the scaffold has been engineered providing unprecedented control of feature size and placement over five orders of magnitude by a combination of electron beam and photolithography. A wide range of micro- and nanotopographies can be incorporated into the scaffold these have been demonstrated to elicit specific cell responses, and utilising a specific topography can enhance the scaffold's final performance.

• Item Type: Articles
• Additional Information: 33rd International Conference on Micro- and Nano-Engineering Copenhagen, DENMARK, SEP 23-26, 2007
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Seunarine, Dr Krishna and Riehle, Dr Mathis and Wilkinson, Professor Christopher and Gadegaard, Professor Nikolaj
• Authors: Seunarine, K., Meredith, D.O., Riehle, M.O., Wilkinson, C.D.W., and Gadegaard, N.
• College/School: College of Science and Engineering > School of Engineering; College of Science and Engineering > School of Engineering > Biomedical Engineering
• Journal Name: Microelectronic Engineering
• ISSN: 0167-9317