IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, (Accepted for Publication)

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Additional Information:RW was supported by Breast Cancer Now (2019DecPhD1349 awarded to SBC). SCE and AK were supported by Cancer Research UK Glasgow Cancer Centre (C596/A25142). Tenovus Scotland (S17-17 awarded to SBC) provided funding for the study. SBC was supported by the Annie McNab Bequest (CRUK Scotland Institute). KB, CM, HH, CH, AH, AM, RS, DW, PJW were supported by Cancer Research UK (A31287, A29799, A29801, DRCPFA-Nov21\100001). CH and AM were supported by CCLG Little Princess Trust Project Grant CCLGA (2020 24). GJG and AH were supported by Wellcome Trust (217093/Z/19/Z) and Medical Research Council (MR/V010972/1). GWJ and DGH were supported by Versus Arthritis (22706). DJP and NS were supported by Biotechnology and Biological Sciences Research Council (BB/R017808/1). MCW, SMC, LW were supported by Sanquin.
Keywords:Cancer, differentiation, T cells, IL-27, innate.
Status:Accepted for Publication
Refereed:Yes
Glasgow Author(s) Enlighten ID:Hay, Dr Jodie and Wiesheu, Robert and Coffelt, Professor Seth and Blyth, Professor Karen and Edwards, Dr Sarah and Miller, Professor Crispin and Michie, Professor Alison and Kilbey, Dr Anna and Graham, Professor Gerard
Authors: Wiesheu, R., Edwards, S. C., Hedley, A., Hall, H., Tosolini, M., da Silva, M. G. F. F., Sumaria, N., Castenmiller, S. M., Wardak, L., Optaczy, Y., Lynn, A., Hill, D. G., Hayes, A. J., Hay, J., Kilbey, A., Shaw, R., Whyte, D., Walsh, P. J., Michie, A. M., Graham, G. J., Manoharan, A., Halsey, C., Blyth, K., Wolkers, M. C., Miller, C., Pennington, D. J., Jones, G. W., Fournie, J.-J., Bekiaris, V., and Coffelt, S.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Cancer Sciences
College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:EMBO Journal
Publisher:EMBO Press
ISSN:0261-4189
ISSN (Online):1460-2075

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
306649Defining chemokine receptor involvement in the myelomonocytic inflammatory responseGerard GrahamWellcome Trust (WELLCOTR)217093/Z/19/ZSII - Immunology & Infection