Simulation of superresolution holography for optical tweezers

Thomson, L.C., Boissel, Y., Whyte, G., Yao, E. and Courtial, J. (2008) Simulation of superresolution holography for optical tweezers. New Journal of Physics, 10(2), 023015. (doi: 10.1088/1367-2630/10/2/023015)

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Abstract

Optical tweezers manipulate microscopic particles using foci of light beams. Their performance is therefore limited by diffraction. Using computer simulations of a model system, we investigate the application of superresolution holography for two-dimensional (2D) light shaping in optical tweezers, which can beat the diffraction limit. We use the direct-search and Gerchberg algorithms to shape the center of a light beam into one or two bright spots; we do not constrain the remainder of the beam. We demonstrate that superresolution algorithms can significantly improve the normalized stiffness of an optical trap and the minimum separation at which neighboring traps can be resolved. We also test if such algorithms can be used interactively, as is desirable in optical tweezers.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Courtial, Dr Johannes and Yao, Dr Eric and Thomson, Ms Laura
Authors: Thomson, L.C., Boissel, Y., Whyte, G., Yao, E., and Courtial, J.
College/School:College of Science and Engineering > School of Physics and Astronomy
Journal Name:New Journal of Physics
ISSN (Online):1367-2630
Published Online:13 February 2008
Copyright Holders:Copyright © 2008 Institute of Physics Publishing Ltd.
First Published:First published in New Journal of Physics 10 (2): 2008
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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