MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground

Tokatlidis, K. (2024) MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground. Cell Reports, 43(3), 113874. (doi: 10.1016/j.celrep.2024.113874) (PMID:38386551)

Abstract

Mitochondria are rich in multi-protein assemblies that are usually dedicated to one function. In this issue of Cell Reports, Horten et al.1 describe a 3-nanometer megacomplex in the mitochondrial inner membrane, which serves multiple functions integrating mitochondria biogenesis and metabolism.

• Item Type: Articles
• Additional Information: The work in the author’s lab was supported by the Biotechnology and Biological Sciences Research Council, United Kingdom (grant number BB/W002892/1).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Tokatlidis, Professor Kostas
• Authors: Tokatlidis, K.
• College/School: College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
• Journal Name: Cell Reports
• Publisher: Elsevier (Cell Press)
• ISSN: 2211-1247
• ISSN (Online): 2211-1247
• Published Online: 21 February 2024
• Copyright Holders: Copyright © 2024 The Authors
• First Published: First published in Cell Reports 43(3):113874
• Publisher Policy: Reproduced under a Creative Commons licence

Project Code	Award No	Project Name	Principal Investigator	Funder's Name	Funder Ref	Lead Dept
313902		Mitochondrial proteostasis and reductive metabolic stress in ageing	Konstantinos Tokatlidis	Biotechnology and Biological Sciences Research Council (BBSRC)	BB/W002892/1	School of Molecular Biosciences