Accelerometer-derived sleep metrics in mild and difficult-to-treat asthma

Sharma, V., Ricketts, H. C., Steffensen, F., Goodfellow, A., Buchan, D. S. and Cowan, D. C. (2024) Accelerometer-derived sleep metrics in mild and difficult-to-treat asthma. Allergy, Asthma and Clinical Immunology, 20, 5. (doi: 10.1186/s13223-024-00874-y) (PMID:38221641) (PMCID:PMC10787977)

Abstract

Introduction: Poor sleep health is associated with increased asthma morbidity and mortality. Accelerometers have been validated to assess sleep parameters though studies using this method in patients with asthma are sparse and none have compared mild to difficult-to-treat asthma populations. Methods: We performed a retrospective analysis from two recent in-house trials comparing sleep metrics between patients with mild and difficult-to-treat asthma. Participants wore accelerometers for 24-hours/day for seven days. Results: Of 124 participants (44 mild, 80 difficult-to-treat), no between-group differences were observed in sleep-window, sleep-time, sleep efficiency or wake time. Sleep-onset time was ~ 40 min later in the difficult-to-treat group (p = 0.019). Discussion: Broadly, we observed no difference in accelerometer-derived sleep-metrics between mild and difficult-to-treat asthma. This is the largest analysis of accelerometer-derived sleep parameters in asthma and the first comparing groups by asthma severity. Sleep-onset initiation may be delayed in difficult-to-treat asthma but a dedicated study is needed to confirm.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Cowan, Douglas and Sharma, Dr Varun
• Authors: Sharma, V., Ricketts, H. C., Steffensen, F., Goodfellow, A., Buchan, D. S., and Cowan, D. C.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: Allergy, Asthma and Clinical Immunology
• Publisher: BioMed Central
• ISSN: 1710-1484
• ISSN (Online): 1710-1492
• Published Online: 14 January 2024
• Copyright Holders: Copyright © 2024 The Authors
• First Published: First published in Allergy, Asthma and Clinical Immunology 20:5
• Publisher Policy: Reproduced under a Creative Commons licence