Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions

Michaelidou, E. E., Kaczmarska, A., Gutierrez Quintana, R. , Morris, J. , Hammond, G. and Cloquell, A. (2024) Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions. Frontiers in Veterinary Science, 11, 1334813. (doi: 10.3389/fvets.2024.1334813)

Abstract

A 7-year-old Lhasa Apso presented with a history of left thoracic limb lameness and neck pain. Magnetic resonance imaging revealed a well-defined, extradural lesion that was hyperintense on T1-weighted (T1W) images and isointense on T2-weighted (T2W) images and T2* images located at the left lamina of the C4 vertebra. Computed tomography showed an isoattenuating and contrast-enhancing mass centered on the left C4 vertebral lamina with associated osteolysis. The mass was surgically debulked, and histopathology revealed a malignant melanocytic tumour. The patient recovered completely and received radiotherapy and three doses of the melanoma vaccine as adjunctive treatment. Eighteen months following treatment, the patient presented with neck pain again, but further investigations were declined at this stage, and the patient was euthanised. To the author’s knowledge, this is the first case report describing the imaging characteristics of a cervical extradural melanocytic tumour in a dog. This case illustrates the MRI and CT imaging features and treatment of a canine melanocytic tumour of the cervical vertebrae.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Cloquell Miro, Dr Ana and Kaczmarska, Mrs Adriana and Morris, Professor Joanna and Gutierrez Quintana, Mr Rodrigo and Michaelidou, Dr Elli and Hammond, Dr Gawain

Creator Roles

Michaelidou, E.: Conceptualization, Software, Writing – original draft, Writing – review and editing
Kaczmarska, A.: Conceptualization, Supervision, Validation, Visualization, Writing – review and editing, Writing – original draft
Gutierrez Quintana, R.: Supervision, Validation, Visualization, Writing – review and editing, Writing – original draft
Morris, J.: Supervision, Validation, Visualization, Writing – review and editing, Writing – original draft
Hammond, G.: Software, Supervision, Validation, Visualization, Writing – review and editing, Writing – original draft
Cloquell Miro, A.: Conceptualization, Supervision, Validation, Visualization, Writing – review and editing, Writing – original draft

• Authors: Michaelidou, E. E., Kaczmarska, A., Gutierrez Quintana, R., Morris, J., Hammond, G., and Cloquell, A.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Frontiers in Veterinary Science
• Publisher: Frontiers Media
• ISSN: 2297-1769
• ISSN (Online): 2297-1769
• Copyright Holders: Copyright © 2024 Michaelidou, Kaczmarska, Gutierrez-Quintana, Morris, Hammond and Cloquell
• First Published: First published in Frontiers in Veterinary Science 11:1334813
• Publisher Policy: Reproduced under a Creative Commons license