Mark, P. B. , Jardine, A. G. and Patel, R. K. (2023) Special populations: chronic kidney disease. In: Clinical Lipidology: A Companion to Braunwald's Heart Disease [3rd ed.]. Series: Companion to Braunwald's Heart Disease series. Elsevier, 367-374.e1. ISBN 9780323882866 (doi: 10.1016/B978-0-323-88286-6.00038-8)
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Abstract
People with chronic kidney disease (CKD) are at increased risk of cardiovascular disease. Reduced kidney function and increased urinary albumin excretion cumulatively increase cardiovascular risk. Although there is a high prevalence of conventional cardiovascular risk factors such as diabetes and hypertension in CKD patients, the additional risk is independent of these. Advanced CKD has a specific dyslipidemia phenotype. Conventional approaches to lipid lowering reduce risk of cardiovascular events in people with CKD who do not require dialysis treatment. In patients with kidney failure treated with dialysis, clinical trials have not shown benefit in lowering low-density lipoprotein cholesterol on risk of cardiovascular events.
| Item Type: | Book Sections |
|---|---|
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Patel, Dr Rajan and Mark, Professor Patrick and Jardine, Professor Alan |
| Authors: | Mark, P. B., Jardine, A. G., and Patel, R. K. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Publisher: | Elsevier |
| ISBN: | 9780323882866 |
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