Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines

Hosie, M.J. , Osborne, R., Yamamoto, J.K., Neil, J.C. and Jarrett, O. (1995) Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines. Journal of Virology, 69(2), pp. 1253-1255.

Abstract

Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Hosie, Professor Margaret and Neil, Professor James
• Authors: Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., and Jarrett, O.
• Subjects: S Agriculture > SF Animal culture > SF600 Veterinary Medicine; Q Science > QR Microbiology > QR355 Virology
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Journal of Virology
• Journal Abbr.: J. Virol.
• ISSN: 0022-538X
• ISSN (Online): 1098-5514