Genome analysis of triploid hybrid Leishmania parasite from the Neotropics

Van den Broeck, F. et al. (2023) Genome analysis of triploid hybrid Leishmania parasite from the Neotropics. Emerging Infectious Diseases, 29(5), pp. 1076-1078. (doi: 10.3201/eid2905.221456) (PMID:37081624) (PMCID:PMC10124652)

Abstract

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

• Item Type: Articles
• Additional Information: F.V.D.B. and S.H. acknowledge support from the Research Foundation Flanders (grant nos. 1226120N and G092921N).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Cotton, Professor James
• Authors: Van den Broeck, F., Heeren, S., Maes, I., Sanders, M., Cotton, J. A., Cupolillo, E., Alvarez, E., Garcia, L., Tasia, M., Marneffe, A., Dujardin, J.-C., and Van der Auwera, G.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Emerging Infectious Diseases
• Publisher: Centers for Disease Control and Prevention
• ISSN: 1080-6040
• ISSN (Online): 1080-6059
• Published Online: 11 April 2023
• Copyright Holders: Materials published in Emerging Infectious Diseases, including text, figures, tables, and photographs are in the public domain and can be reprinted or used without permission with proper citation.
• First Published: First published in Emerging Infectious Diseases 29(5):1076-1078
• Publisher Policy: Reproduced in accordance with the publisher copyright policy