Remote exercise testing in pulmonary hypertension (PHRET)

Stubbs, H., Lua, S., Ingram, J., Jani, B. D. , Brewis, M., Church, C. and Johnson, M. (2023) Remote exercise testing in pulmonary hypertension (PHRET). Pulmonary Circulation, 13(4), e12325. (doi: 10.1002/pul2.12325) (PMID:38148951) (PMCID:PMC10749888)

Abstract

Remote exercise tests for patients with pulmonary hypertension (PH) would improve the telemedicine strategies in this disease. The PHRET study assessed the validity and feasibility of four remote exercise tests performed by PH patients at home. Participants undergoing diagnostic assessment for PH were included. At baseline, patients completed a 6MWT followed by a range of study tests including a Timed Up and Go (TUG) test, a Sit-to-Stand (STS), a Step Test (ST), and a tele-6MWT (T6MWT) performed outside using a GPS-enabled smartphone. Patients performed these tests at home following discharge and at first follow-up. Analysis focused on comparing the results of study tests to the standard 6MWT. The discontinuation rate was 15%. Ninety-seven percent of patients were able to complete a TUG, 92% a STS, 73% a ST, and 49% a T6MWT. At baseline, correlation between the standard 6MWT and study tests, respectively, was T6MWT 0.93, ST 0.78, STS 0.71, and TUG −0.76 (p < 0.001). Direction of change in the study test agreed with the standard 6MWT in 68% of the follow-up ST, 68% of the STS, 71% of the TUG, and 79% of the T6MWT. Patients were able to complete the tests at home, there were no adverse incidents and ≥92% of patients were happy to continue performing home tests. Remote exercise testing is feasible. The T6MWT was a valid remote measure of exercise capacity, but could only be performed by a limited number of patients. The high discontinuation rate may impact the utility of remote tests.

• Item Type: Articles
• Status: Published
• Refereed: No
• Glasgow Author(s) Enlighten ID: Jani, Dr Bhautesh and Lua, Dr Stephanie and Stubbs, Harrison and Brewis, Dr Melanie and Church, Dr Colin

Creator Roles

Stubbs, H.: Methodology, Formal analysis, Investigation, Data curation, Writing – original draft, Visualization
Lua, S.: Writing – review and editing
Jani, B.: Supervision, Writing – review and editing
Brewis, M.: Supervision, Writing – review and editing
Church, C.: Supervision, Writing – review and editing

• Authors: Stubbs, H., Lua, S., Ingram, J., Jani, B. D., Brewis, M., Church, C., and Johnson, M.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care
• Journal Name: Pulmonary Circulation
• Publisher: Wiley
• ISSN: 2045-8932
• ISSN (Online): 2045-8940
• Copyright Holders: Copyright: © 2023 The Authors
• First Published: First published in Pulmonary Circulation 13(4): e12325
• Publisher Policy: Reproduced under a Creative Commons licence