Diagnostic laparoscopy to investigate unexplained lactic acidosis in critically ill patients - a descriptive single centre cohort study

Sajid, M. A., Khan, K. S. and Hanif, Z. (2018) Diagnostic laparoscopy to investigate unexplained lactic acidosis in critically ill patients - a descriptive single centre cohort study. Annals of Medicine and Surgery, 36, pp. 231-234. (doi: 10.1016/j.amsu.2018.11.008) (PMID:30519464) (PMCID:PMC6260236)

Abstract

Introduction: Unexplained lactic acidosis (LA) in a critically ill patient often prompts investigations to rule out any reversible intra-abdominal cause. Equivocal results can lead to an emergency laparotomy (EL) with subsequent high morbidity and mortality rates. Our objective was to determine the clinical impact of urgent diagnostic laparoscopy (UDL) in such patients. Methods: This was a descriptive single-centre cohort study. UDL on 28 consecutive critically ill patients with unexplained LA who were referred to a single surgeon over 16 years period were analysed. UDL was proformed either at bedside or in theatre without prior computerised tomography (CT) scan. Patient's demographics, ASA grade, referral route and intraoperative findings were analysed. Results: Eighteen patients underwent bedside UDL in the critical care setting and further 10 had UDL in theatre. Fourteen patients had normal UDL, out of these 10 had LA secondary to low cardiac output states. Fourteen patients had positive UDL findings. Seven patients had features of mesenteric ischaemia, two had gangrenous gallbladder, two had hepatic ischaemia, one patient had acute pancreatitis, one had gangrenous uterus and one had gastric volvulus. Five of the 14 patients with positive UDL were converted to laparotomy for definitive management. In total, of the 28 patients in the cohort, 23 patients avoided EL. Conclusion: UDL is useful and feasible investigation for unexplained LA in the critically ill patients and it can avoid unnecessary EL in many patients. We would recommend the use of UDL as a safe and feasible investigation in such patients.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Khan, Mr Khurram

Creator Roles

Khan, K.: Data curation, Writing – original draft

• Authors: Sajid, M. A., Khan, K. S., and Hanif, Z.
• College/School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Annals of Medicine and Surgery
• Publisher: Elsevier Ltd on behalf of IJS Publishing Group Ltd
• ISSN: 2049-0801
• ISSN (Online): 2049-0801
• Copyright Holders: Crown Copyright © 2018
• First Published: First published in Annals of Medicine and Surgery 36:231-234
• Publisher Policy: Reproduced under a Creative Commons license