Impact of adult weight management interventions on mental health: a systematic review and meta-analysis protocol

Jones, R. A., Lawlor, E. R. , Griffin, S. J., van Sluijs, E. M.F. and Ahern, A. L. (2020) Impact of adult weight management interventions on mental health: a systematic review and meta-analysis protocol. BMJ Open, 10(1), e031857. (doi: 10.1136/bmjopen-2019-031857) (PMID:31964665) (PMCID:PMC7045146)

Abstract

Introduction: The effects of interventions targeting weight loss on physical health are well described, yet the evidence for mental health is less clear. It is essential to better understand the impact of weight management interventions on mental health to optimise care and minimise risk of harm. We will assess the effect of behavioural weight management interventions on mental health in adults with overweight and obesity. Methods and analysis: The systematic review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance. We will include behavioural weight management interventions with a diet and/or physical activity component focusing on weight loss for adults with a body mass index ≥25 kg/m2. Randomised controlled trials (RCTs) and cluster RCTs will be the only eligible study designs. Outcomes of interest will be related to mental health. The following databases were searched from inception to 07 May 2019: MEDLINE, Embase, Cochrane database (CENTRAL), PsycINFO, ASSIA, AMED and CINAHL. The search strategy was based on four concepts: (1) adults, defined as ≥18 years, with overweight/obesity, defined as BMI ≥25kg/m², (2) weight management interventions, (3) mental health outcomes and (4) study design. The search was restricted to English-language published papers, with no other restrictions applied. Two stage screening for eligibility will be completed by two independent reviewers, with two independent reviewers completing data extraction and risk of bias assessment. Data permitting, a random-effects meta-analysis of outcomes, subgroup analyses and meta-regression will be conducted. If not appropriate, narrative synthesis and 'levels of evidence' assessment will be completed.

• Item Type: Articles
• Additional Information: g RAJ, ERL, ALA and SJG are supported by the Medical Research Council (MRC) (Grant MC_UU_12015/4). The University of Cambridge has received salary support in respect of SJG from the National Health Service in the East of England through the Clinical Academic Reserve. EMFvS is supported by the Medical Research Council (MRC) (Grant MC_UU_12015/7).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Lawlor, Dr Emma
• Authors: Jones, R. A., Lawlor, E. R., Griffin, S. J., van Sluijs, E. M.F., and Ahern, A. L.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
• Journal Name: BMJ Open
• Publisher: BMJ Publishing Group
• ISSN: 2044-6055
• ISSN (Online): 2044-6055
• Published Online: 20 January 2020
• Copyright Holders: Copyright © Author(s) (or their employer(s)) 2020
• First Published: First published in BMJ Open 10(1):e031857
• Publisher Policy: Reproduced under a Creative Commons licence