Certainty of the Global Burden of Disease 2019 modelled prevalence estimates for musculoskeletal conditions: a meta-epidemiological study

Muñoz Laguna, J., Puhan, M. A., Rodríguez Artalejo, F., De Pauw, R., Wyper, G. M.A. , Devleesschauwer, B., Santos, J. V. and Hincapié, C. A. (2023) Certainty of the Global Burden of Disease 2019 modelled prevalence estimates for musculoskeletal conditions: a meta-epidemiological study. International Journal of Public Health, 68, 1605763. (doi: 10.3389/ijph.2023.1605763) (PMID:37325175) (PMCID:PMC10266422)

Abstract

Objectives: To describe and assess the risk of bias of the primary input studies that underpinned the Global Burden of Disease Study (GBD) 2019 modelled prevalence estimates of low back pain (LBP), neck pain (NP), and knee osteoarthritis (OA), from Australia, Brazil, Canada, Spain, and Switzerland. To evaluate the certainty of the GBD modelled prevalence evidence. Methods: Primary studies were identified using the GBD Data Input Sources Tool and their risk of bias was assessed using a validated tool. We rated the certainty of modelled prevalence estimates based on the GRADE Guidelines 30―the GRADE approach for modelled evidence. Results: Seventy-two primary studies (LBP: 67, NP: 2, knee OA: 3) underpinned the GBD estimates. Most studies had limited representativeness of their study populations, used suboptimal case definitions and applied assessment instruments with unknown psychometric properties. The certainty of modelled prevalence estimates was low, mainly due to risk of bias and indirectness. Conclusion: Beyond the risk of bias of primary input studies for LBP, NP, and knee OA in GBD 2019, the certainty of country-specific modelled prevalence estimates still have room for improvement.

• Item Type: Articles
• Additional Information: This work was supported, in part, by the European Cooperation in Science and Technology (COST Action CA18218 virtual mobility grant No CA18218-6a68cbf4).
• Keywords: GRADE approach, prevalence, knee osteoarthritis, neck pain, global burden of disease, epidemiology, musculoskeletal disorders, low back pain.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Wyper, Dr Grant
• Authors: Muñoz Laguna, J., Puhan, M. A., Rodríguez Artalejo, F., De Pauw, R., Wyper, G. M.A., Devleesschauwer, B., Santos, J. V., and Hincapié, C. A.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care
• Journal Name: International Journal of Public Health
• Publisher: Frontiers Media
• ISSN: 1661-8556
• ISSN (Online): 1661-8564
• Copyright Holders: Copyright © 2023 Muñoz Laguna, Puhan, Rodríguez Artalejo, De Pauw, Wyper, Devleesschauwer, Santos and Hincapié
• First Published: First published in International Journal of Public Health 68: 1605763
• Publisher Policy: Reproduced under a Creative Commons License