Initial weight loss and early intervention adherence predict long-term weight loss during the PROPEL lifestyle intervention

Höchsmann, C. et al. (2023) Initial weight loss and early intervention adherence predict long-term weight loss during the PROPEL lifestyle intervention. Obesity, 31(9), pp. 2272-2282. (doi: 10.1002/oby.23854) (PMID:37551762)

Abstract

Objective: This study tested whether initial weight change (WC), self-weighing, and adherence to the expected WC trajectory predict longer-term WC in an underserved primary-care population with obesity. Methods: Data from the intervention group (n = 452; 88% women; 74% Black; BMI 37.3 kg/m2 [SD: 4.6]) of the Promoting Successful Weight Loss in Primary Care in Louisiana trial were analyzed. Initial (2-, 4-, and 8-week) percentage WC was calculated from baseline clinic weights and daily at-home weights. Weights were considered adherent if they were on the expected WC trajectory (10% at 6 months with lower [7.5%] and upper [12.5%] bounds). Linear mixed-effects models tested whether initial WC and the number of daily and adherent weights predicted WC at 6, 12, and 24 months. Results: Percentage WC during the initial 2, 4, and 8 weeks predicted percentage WC at 6 (R2 = 0.15, R2 = 0.28, and R2 = 0.50), 12 (R2 = 0.11, R2 = 0.19, and R2 = 0.32), and 24 (R2 = 0.09, R2 = 0.11, and R2 = 0.16) months (all p < 0.01). Initial daily and adherent weights were significantly associated with WC as individual predictors, but they only marginally improved predictions beyond initial weight loss alone in multivariable models. Conclusions: These results highlight the importance of initial WC for predicting long-term WC and show that self-weighing and adherence to the expected WC trajectory can improve WC prediction.

• Item Type: Articles
• Additional Information: The research reported in this article was funded through a Patient-Centered Outcomes Research Institute (PCORI) award (OB-1402-10977).
• Keywords: initial weight loss, adherence, intensive lifestyle intervention, underserved, primary care
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Dorling, Dr James
• Authors: Höchsmann, C., Martin, C. K., Apolzan, J. W., Dorling, J. L., Newton Jr., R. L., Denstel, K. D., Mire, E. F., Johnson, W. D., Zhang, D., Arnold, C. L., Davis, T. C., Fonseca, V., Thethi, T. K., Lavie, C. J., Springgate, B., and Katzmarzyk, P. T.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Obesity
• Publisher: Wiley
• ISSN: 1930-7381
• ISSN (Online): 1930-739X
• Published Online: 08 August 2023
• Copyright Holders: Copyright © 2023 The Obesity Society
• First Published: First published in Obesity 31(9):2272-2282
• Publisher Policy: Reproduced in accordance with the publisher copyright policy