PF-431396 hydrate inhibition of kinase phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release

Li, X., Ormsby, M. J., Fallata, G., Meikle, L. M., Walker, D. , Xu, D. and Wall, D. M. (2023) PF-431396 hydrate inhibition of kinase phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release. Microbiology, 169(6), 001337. (doi: 10.1099/mic.0.001337) (PMID:37311220) (PMCID:PMC10333790)

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Abstract

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Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Walker, Professor Daniel and Xu, Dr Damo and Meikle, Dr Lynsey and Ormsby, Dr Michael and LI, XIANG and Wall, Dr Daniel and Fallata, Ghaith
Authors: Li, X., Ormsby, M. J., Fallata, G., Meikle, L. M., Walker, D., Xu, D., and Wall, D. M.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Microbiology
Publisher:Microbiology Society
ISSN:1350-0872
ISSN (Online):1465-2080
Published Online:13 June 2023
Copyright Holders:Copyright © 2023 The Authors
First Published:First published in Microbiology 169(6):001337
Publisher Policy:Reproduced under a Creative Commons license

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
167488Survival and dissemination of enteric pathogens through exploitation and inhibition of programmed cell death pathways in circulating immune cells.Daniel WallBiotechnology and Biological Sciences Research Council (BBSRC)BB/K008005/1III - Bacteriology
173261Propionic acid use in agriculture and food production is driving evolution of novel Escherichia coli pathotypesDaniel WallBiotechnology and Biological Sciences Research Council (BBSRC)BB/P003281/1III - Bacteriology