Fornace, K. M. et al. (2023) Simian malaria: a narrative review on emergence, epidemiology and threat to global malaria elimination. Lancet Infectious Diseases, 23(12), E520-E520. (doi: 10.1016/S1473-3099(23)00298-0) (PMID:37454671)
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Abstract
Simian malaria from wild non-human primate populations is increasingly recognised as a public health threat and is now the main cause of human malaria in Malaysia and some regions of Brazil. In 2022, Malaysia became the first country not to achieve malaria elimination due to zoonotic simian malaria. We review the global distribution and drivers of simian malaria and identify priorities for diagnosis, treatment, surveillance, and control. Environmental change is driving closer interactions between humans and wildlife, with malaria parasites from non-human primates spilling over into human populations and human malaria parasites spilling back into wild non-human primate populations. These complex transmission cycles require new molecular and epidemiological approaches to track parasite spread. Current methods of malaria control are ineffective, with wildlife reservoirs and primarily outdoor-biting mosquito vectors urgently requiring the development of novel control strategies. Without these, simian malaria has the potential to undermine malaria elimination globally.
| Item Type: | Articles |
|---|---|
| Additional Information: | KMF is supported by a Sir Henry Dale fellowship, jointly funded by the Wellcome Trust and Royal Society (grant number 221963/Z/20/Z). GZL is supported by the São Paulo Research Foundation (grant number 2021/06669-6). IV, AA, and YLL were funded by the Ministry of Higher Education of Malaysia Long Term Research Grant Scheme (grant numbers LRGS 1/2018/UM/01/1/2, LRGS 1/2018/UM/01/1/3, and LRGS 1/2018/UM/01/1/4). |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Fornace, Dr Kimberly |
| Authors: | Fornace, K. M., Laporta, G. Z., Vythilingham, I., Chua, T. H., Ahmed, K., Jeyaprakasam, N. K., Ribeiro de Castro Duarte, A. M., Amir, A., Phang, W. K., Drakeley, C., Sallum, M. A. M., and Lau, Y. L. |
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Lancet Infectious Diseases |
| Publisher: | Elsevier |
| ISSN: | 1473-3099 |
| ISSN (Online): | 1474-4457 |
| Published Online: | 13 July 2023 |
| Copyright Holders: | Copyright © 2023 Elsevier Ltd. |
| First Published: | First published in Lancet Infectious Diseases 23(12):E520-E532 |
| Publisher Policy: | Reproduced with the permission of the publisher |
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