Cheong, Y. L. et al. (2023) Spatial distribution and long-term persistence of Wolbachia-infected Aedes aegypti in the Mentari Court, Malaysia. Insects, 14(4), 373. (doi: 10.3390/insects14040373) (PMID:37103189) (PMCID:PMC10146232)
![[img]](https://eprints.gla.ac.uk/style/images/fileicons/text.png) |
Text
296918.pdf - Published Version Available under License Creative Commons Attribution. 3MB |
Abstract
Dengue is endemic in Malaysia, and vector control strategies are vital to reduce dengue transmission. The Wolbachia strain wAlbB carried by both sexes of Ae. aegypti was released in Mentari Court, a high-rise residential site, in October 2017 and stopped after 20 weeks. Wolbachia frequencies are still being monitored at multiple traps across this site, providing an opportunity to examine the spatiotemporal distribution of Wolbachia and mosquito density with respect to year, residential block, and floor, using spatial interpolation in ArcGIS, GLMs, and contingency analyses. In just 12 weeks, Wolbachia-infected mosquitoes were established right across the Mentari Court site with an overall infection frequency of >90%. To date, the Wolbachia frequency of Ae. aegypti has remained high in all areas across the site despite releases finishing four years ago. Nevertheless, the Wolbachia invaded more rapidly in some residential blocks than others, and also showed a relatively higher frequency on the eighth floor. The Ae. aegypti index tended to differ somewhat between residential blocks, whilst the Ae. albopictus index was relatively higher at the top and bottom floors of buildings. In Mentari Court, only a short release period was required to infiltrate Wolbachia completely and stably into the natural population. The results inform future releases in comparable sites in a dengue control programme.
| Item Type: | Articles |
|---|---|
| Additional Information: | The primary funding for the study was provided by Wellcome Trust Award 108508, with additional funding from Wellcome Trust Award 202888 and funding from the Ministry of Health Malaysia NMRR-16-297-28898. |
| Keywords: | Spatial interpolation, Ae. aegypti, Wolbachia, ovitrap index, invasion. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Sinkins, Professor Steven |
| Authors: | Cheong, Y. L., Nazni, W. A., Lee, H. L., NoorAfizah, A., MohdKhairuddin, I. C., Kamarul, G. M. R., Nizam, N. M. N., Arif, M. A. K., NurZatilAqmar, Z. M., Irwan, S. M., Khadijah, K., Paid, Y. M., Topek, O., Hasnor, A. H., AbuBakar, R., Singh Gill, B., Fadzilah, K., Tahir, A., Sinkins, S. P., and Hoffmann, A. A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Insects |
| Publisher: | MDPI |
| ISSN: | 2075-4450 |
| ISSN (Online): | 2075-4450 |
| Published Online: | 11 April 2023 |
| Copyright Holders: | Copyright © 2023 The Authors |
| First Published: | First published in Insects 14(4): 373 |
| Publisher Policy: | Reproduced under a Creative Commons License |
| Data DOI: | 10.17632/sr2vppg24f.1 |
University Staff: Request a correction | Enlighten Editors: Update this record
Funder and Project Information
Funder and Project Information