Survivorship of high tibial osteotomy in the treatment of osteoarthritis of the knee: a retrospective cohort study with fourteen years’ follow-up

Bhattacharyya, R., Alloush, A., Wilson, C., Doonan, J. , Rooney, B., Walker, C., Maclean, A. and Blyth, M. (2023) Survivorship of high tibial osteotomy in the treatment of osteoarthritis of the knee: a retrospective cohort study with fourteen years’ follow-up. International Orthopaedics, 47(7), pp. 1765-1770. (doi: 10.1007/s00264-023-05802-0) (PMID:37039819)

Abstract

Purpose: This study was to evaluate the survivorship of HTO for the treatment of medial compartment osteoarthritis (OA) in young and active patients from two teaching hospitals in a single city. Methods: This is a retrospective cohort multicenter study looking at HTO for treatment of medial compartment OA. We analyzed a case series of HTO’s performed by four surgeons in two centres over a 14-year period. Failure was defined as conversion to total knee replacement (TKR). All cases where additional procedures for instability of the knee were performed at the time of the index surgery were excluded. Time to failure was recorded, and a Kaplan-Meir (KM) analysis was performed to evaluate survivorship. Univariate binary regression analysis was undertaken to identify associations between risk factors and failure. Results: A total of 96 patients were included in the study with a median age was 45 years. The survivorship at five years post-op was 90.3%, and at ten years post-op, it was 82%. Patients that were 14 years after surgery had a survivorship of 65%. Also, 18.8% of patients required the removal of their metalwork. The overall complication rate was 6.3%. The univariate regression analysis showed that higher age (p = 0.02) and larger corrections requiring the use of bone graft increased the risk of failure (p = 0.02). There was no statistically significant correlation between laterality, gender, complication rate, and pre-operative alignment to survivorship. Conclusion: This is one of the largest reported case series of HTO’s with comparable survivorship at five and ten year follow-up compared to the reported literature. There was an association found between increasing age and larger corrections requiring bone graft at index procedure to increasing failure rate.

• Item Type: Articles
• Keywords: High Tibial Osteotomy, HTO, survivorship, medial compartment osteoarthritis
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Walker, Mr Colin and Blyth, Mr Mark and Doonan, Dr James
• Authors: Bhattacharyya, R., Alloush, A., Wilson, C., Doonan, J., Rooney, B., Walker, C., Maclean, A., and Blyth, M.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: International Orthopaedics
• Publisher: Springer
• ISSN: 0341-2695
• ISSN (Online): 1432-5195
• Published Online: 11 April 2023
• Copyright Holders: Copyright © 2023, The Author(s) under exclusive licence to SICOT aisbl
• First Published: First published in International Orthopaedics 47(7):1765-1770
• Publisher Policy: Reproduced in accordance with the publisher copyright policy