Guidance on the use of complex systems models for economic evaluations of public health interventions

Breeze, P. R. et al. (2023) Guidance on the use of complex systems models for economic evaluations of public health interventions. Health Economics, 32(7), pp. 1603-1625. (doi: 10.1002/hec.4681) (PMID:37081811)

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Abstract

To help health economic modelers respond to demands for greater use of complex systems models in public health. To propose identifiable features of such models and support researchers to plan public health modeling projects using these models. A working group of experts in complex systems modeling and economic evaluation was brought together to develop and jointly write guidance for the use of complex systems models for health economic analysis. The content of workshops was informed by a scoping review. A public health complex systems model for economic evaluation is defined as a quantitative, dynamic, non-linear model that incorporates feedback and interactions among model elements, in order to capture emergent outcomes and estimate health, economic and potentially other consequences to inform public policies. The guidance covers: when complex systems modeling is needed; principles for designing a complex systems model; and how to choose an appropriate modeling technique. This paper provides a definition to identify and characterize complex systems models for economic evaluations and proposes guidance on key aspects of the process for health economics analysis. This document will support the development of complex systems models, with impact on public health systems policy and decision making.

Item Type:Articles
Additional Information:This project is funded by the National Institute for Health Research (NIHR) School for Public Health Research (SPHR) (Grant Reference Number PD-SPH-2015). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. Robert Smith, Thomas Bayley, Jennifer Boyd, and Kate Hayes received funding from the University of Sheffield Wellcome Trust Doctoral Training Center (203956/Z/16/Z). Amanda Karapici is supported by the NIHR School for Public Health Research Doctoral Studentship. Chris Jackson is supported by the Medical Research Council, program number MRC_MC_UU_00002/11. Eric Silverman is funded by the Medical Research Councl (MC_UU_00022/1), and UK Prevention Research Partnership (MR/S037594/1). Frank DeVocht is partly funded by the National Institute for Health Research Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. Petra Meier is funded by the UKRI Medical Research Council and UKRI Medical Research Council UK Prevention Research Partnership. Robin Purshouse is funded by the National Institutes of Health, R01 AA024443. Lion Shahab is funded by Cancer Research UK (C1417/A22962). Peter Scarborough is funded from a fellowship from the British Heart Foundation (FS/15/34/31656). Visakan Kadirkamanathan is supported by the UK-PRP SIPHER Project.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Silverman, Dr Eric and Lawson, Mr Kenny and Meier, Professor Petra and Boyd, Dr Jennifer and Briggs, Professor Andrew
Authors: Breeze, P. R., Squires, H., Ennis, K., Meier, P., Hayes, K., Lomax, N., Shiell, A., Kee, F., de Vocht, F., O'Flaherty, M., Gilbert, N., Purshouse, R., Robinson, S., Dodd, P. J., Strong, M., Paisley, S., Smith, R., Briggs, A., Shahab, L., Occhipinti, J.-A., Lawson, K., Bayley, T., Smith, R., Boyd, J., Kadirkamanathan, V., Cookson, R., Hernandez-Alava, M., Jackson, C. H., Karapici, A., Sassi, F., Scarborough, P., Siebert, U., Silverman, E., Vale, L., Walsh, C., and Brennan, A.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment
College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > MRC/CSO SPHSU
Journal Name:Health Economics
Publisher:Wiley
ISSN:1057-9230
ISSN (Online):1099-1050
Published Online:20 April 2023
Copyright Holders:Copyright © 2023 The Authors
First Published:First published in Health Economics 32(7):1603-1625
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
313944System-science Informed Public Health and Economic Research for non-communicable Disease Prevention (the SIPHER consortium)Petra MeierMedical Research Council (MRC)MR/S037578/2SHW - MRC/CSO Social & Public Health Sciences Unit
3048230011Complexity in healthSharon SimpsonMedical Research Council (MRC)MC_UU_00022/1HW - MRC/CSO Social and Public Health Sciences Unit
303087PHASE: The Population HeAlth Simulation nEtworkLaurence MooreMedical Research Council (MRC)MR/S037594/1SHW - MRC/CSO Social & Public Health Sciences Unit