World Workshop on Oral Medicine VIII: development of a core outcome set for oral lichen planus: a consensus study

López-Pintor, R. M. et al. (2023) World Workshop on Oral Medicine VIII: development of a core outcome set for oral lichen planus: a consensus study. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 135(6), pp. 792-803. (doi: 10.1016/j.oooo.2023.01.013) (PMID:37061409)

Abstract

Objective: A core outcome set (COS) is the minimum agreed data set required to be measured in interventional trials. To date, there is no COS for oral lichen planus (OLP). This study aims to show the final consensus project which brings together the results of the previous stages and how the COS for OLP was developed. Study Design: Fifteen outcome domains were previously identified following a systematic review of existing interventional studies on OLP and a qualitative study involving patients with this condition. Delphi-style clicker sessions were conducted at the World Workshop on Oral Medicine VIII and the 2022 American Academy of Oral Medicine Annual Conference. Following this, OLP patients from the Oral Medicine unit of the University of Cork, Ireland, also completed the process. A further round of interactive consensus led to the final COS. Results: The consensus processes led to a COS of 11 outcome domains to be measured in future trials on OLP. Conclusion: A COS is developed by consensus to help reduce the heterogeneity of outcomes measured in interventional trials. This will allow future pooling of outcomes and data for meta-analyses. The consensus process followed the Core Outcome Measures in Effectiveness Trials (COMET) guidelines and involved the agreement of relevant stakeholders, including patients with OLP. This project shows a methodology that could be used for future COS development.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Taylor, Dr Jennifer
• Authors: López-Pintor, R. M., Diniz-Freitas, M., Ramesh, S. S. K., Valdéz, J. A., Bissonnette, C., Dan, H., Brennan, M. T., Burkhart, N. W., Greenberg, M. S., Farag, A., Hong, C., Sollecito, T. P., Setterfield, J. F., Woo, S.-B., Ni Riordain, R., Robledo-Sierra, J., and Taylor, J.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
• Journal Name: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
• Publisher: Elsevier
• ISSN: 2212-4403
• ISSN (Online): 2212-4411
• Published Online: 03 March 2023
• Copyright Holders: Copyright © 2023 Elsevier Inc.
• First Published: First published in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 135(6):792-803
• Publisher Policy: Reproduced under a Creative Commons License