Treadwell, R., de Moliner, F., Subiros-Funosas, R., Hurd, T., Knox, K. and Vendrell, M. (2018) A fluorescent activatable probe for imaging intracellular Mg2+. Organic and Biomolecular Chemistry, 16(2), pp. 239-244. (doi: 10.1039/C7OB02965A) (PMID:29256562) (PMCID:PMC5789582)
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Abstract
An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg2+ without interference from Ca2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Knox, Dr Kirsten |
| Authors: | Treadwell, R., de Moliner, F., Subiros-Funosas, R., Hurd, T., Knox, K., and Vendrell, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
| Journal Name: | Organic and Biomolecular Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1477-0520 |
| ISSN (Online): | 1477-0539 |
| Published Online: | 19 December 2017 |
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