Analysing Cancer Genomics in the Elastic Cloud

Smowton, C., Miller, C. , Xing, W., Balla, A., Antoniades, D., Pallis, G. and Dikaiakos, M. D. (2015) Analysing Cancer Genomics in the Elastic Cloud. In: 2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, Shenzhen, China, 4-7 May 2015, pp. 835-844. (doi: 10.1109/CCGrid.2015.176)

Abstract

With the rapidly growing demand for DNA analysis, the need for storing and processing large-scale genome data has presented significant challenges. This paper describes how the Genome Analysis Toolkit (GATK) can be deployed to an elastic cloud, and defines policy to drive elastic scaling of the application. We extensively analyse the GATK to expose opportunities for resource elasticity, demonstrate that it can be practically deployed at scale in a cloud environment, and demonstrate that applying elastic scaling improves the performance to cost tradeoff achieved in a simulated environment.

• Item Type: Conference Proceedings
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Miller, Professor Crispin
• Authors: Smowton, C., Miller, C., Xing, W., Balla, A., Antoniades, D., Pallis, G., and Dikaiakos, M. D.
• College/School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences