Sohn, H., Sweeney, S., Mudzengi, D., Creswell, J., Menzies, N.A., Fox, G.J., MacPherson, P. and Dowdy, D.W. (2021) Determining the value of TB active case-finding: current evidence and methodological considerations. International Journal of Tuberculosis and Lung Disease, 25(3), pp. 171-181. (doi: 10.5588/ijtld.20.0565) (PMID:33688805) (PMCID:PMC9333998)
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Abstract
Active case-finding (ACF) is an important component of the End TB Strategy. However, ACF is resource-intensive, and the economics of ACF are not well-understood. Data on the costs of ACF are limited, with little consistency in the units and methods used to estimate and report costs. Mathematical models to forecast the long-term effects of ACF require empirical measurements of the yield, timing and costs of case detection. Pragmatic trials offer an opportunity to assess the cost-effectiveness of ACF interventions within a ‘real-world´ context. However, such analyses generally require early introduction of economic evaluations to enable prospective data collection on resource requirements. Closing the global case-detection gap will require substantial additional resources, including continued investment in innovative technologies. Research is essential to the optimal implementation, cost-effectiveness, and affordability of ACF in high-burden settings. To assess the value of ACF, we must prioritize the collection of high-quality data regarding costs and effectiveness, and link those data to analytical models that are adapted to local settings.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | MacPherson, Professor Peter |
Authors: | Sohn, H., Sweeney, S., Mudzengi, D., Creswell, J., Menzies, N.A., Fox, G.J., MacPherson, P., and Dowdy, D.W. |
College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health |
Journal Name: | International Journal of Tuberculosis and Lung Disease |
Publisher: | International Union against Tuberculosis and Lung Disease |
ISSN: | 1027-3719 |
ISSN (Online): | 1815-7920 |
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