Baer, H. M., Sandilya, S. and Steiner, T. S. (2023) Evading the Toll booth: how "silent" flagellins may bind yet fail to activate TLR5. Science Immunology, 8(79), eadf0244. (doi: 10.1126/sciimmunol.adf0244) (PMID:36608148)
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Abstract
The nature of flagellin-Toll-like receptor 5 (TLR5) interactions, depending on binding to and activation of TLR5, may hold a key to the distinct differences in gut microbiome and intestinal immune function in different populations around the world (see related Research Article by Clasen et al.).
| Item Type: | Articles |
|---|---|
| Keywords: | Toll-like receptor 5, intestines, flagellin - metabolism. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Baer, Hannah |
| Creator Roles: | Baer, H. M.Conceptualization, Funding acquisition, Visualization, Writing – original draft, Writing – review and editing |
| Authors: | Baer, H. M., Sandilya, S., and Steiner, T. S. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Science Immunology |
| Publisher: | American Association for the Advancement of Science |
| ISSN: | 2470-9468 |
| ISSN (Online): | 2470-9468 |
| Published Online: | 06 January 2023 |
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